The medical advances during the 20th Century have contributed to some of the most significant milestones in history. Transplantation in particular has seen many developments since the first operation in 1905 when a cornea was successfully transplanted. Since then, blood transfusion has been established (in 1918) and the first kidney transplant took place in the same year. Even more amazing, the first heart transplant took place over 35 years ago in 1967.

This December saw the latest milestone in UK transplant history with the 10 millionth potential donor being added to the National Organ Donor Register. Each year organ donation gives more than 2,700 people in the UK a new lease of life. The register, which was launched in 1994, allows a positive record of a person's wishes and makes it easier for relatives to agree to organ donation. Those wishing to register can opt for any part of their body or for specific organs only - kidneys, lungs, liver, pancreas and corneas. People can also have their details removed from the register or amended at any time.

Even with the latest landmark in organ donation there is still a chronic shortage of organs for transplant with more than 5,600 people in the UK still on the waiting list. Last year alone nearly 400 people died while waiting. Without an increase in organ donation, one in ten people waiting for a heart transplant will die and many others will continue to lose their lives before they even get onto the waiting list.

UK Transplant is committed to increasing the number on the NHS Organ Donor Register to 16 million by 2010 so it is vital that people sign up and give the ultimate show of support.

One recently established initiative to further stimulate public awareness is local councils including donor information documents with annual electoral registration forms. Organ Donor Registration Forms are also sent out to new drivers by the DVLA and forms are available from GP's surgeries, hospitals or by calling 0845 60 60 400.

Sue Sutherland, Chief Executive of UK Transplant said "We would like to thank all those who, by putting their names on the register, are offering others the most precious gift of all - the gift of life. This is a real landmark in organ donation and transplantation but we know that many more lives could be saved if more people joined the register and discussed their wishes with their family".

To find out more about how you can help save lives by becoming a donor visit www.uktransplant.org.uk.